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Miscarriage Causes and How to Test Each of Them

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Causes of miscarriage can not always be clearly defined. The most common causes of miscarriage in the first trimester are chromosomal abnormalities, collagen vascular diseases (such as lupus), diabetes, other hormonal problems, infections and birth defects of the uterus.
Chromosomal abnormalities associated with the fruit are among the most common causes of miscarriage in early pregnancy.

Chromosomes are microscopic components of cells that carry the entire genetic material that determines the color of both hair and eyes, and the overall appearance and body structure of the child. These chromosomes are doubled and split repeatedly during development of the embryo, and at each stage of the process can be a problem. A type of genetic abnormalities are predominant in couples who are experiencing similar mode of expression miscarriages. These genetic characteristics can be detected by blood tests that are done prior to the beginning of attempts to get pregnant. Half of fetal tissue from spontaneous abortions in the first trimester of pregnancy include damaged chromosomes. These values âEUR
Chromosomal abnormalities are becoming more prevalent with age.

That is why to younger women, aged over 35 years are at higher risk of miscarriage. Advanced age carries a significant risk of miscarriage in early pregnancy in otherwise physically healthy women.

Collagen vascular diseases are diseases in which the patient's immune system attacks his own organs. These diseases can have extremely serious nature both during and between two consecutive pregnancies. In such a condition the woman's body produces antibodies against its own body tissues.

Examples of a collagen vascular disorders that are associated with increased risk of miscarriage are systemic lupus erythematosus and antiphospholipid antibody syndrome. By making the blood test can confirm the presence of an excessive amount of antibodies, and these tests are normally used for the diagnosis of the aforementioned conditions.

In general, diabetes can be controlled during pregnancy, especially when specialist monitors the status of their patient. But when diabetes can not be controlled adequately the risk of miscarriage increases rapidly, and the probability the baby to be born with major defects is greater. There are other problems that may arise in connection with diabetes during pregnancy, so the control of blood sugar levels is extremely important.

There hormonal factors, which may be associated with an increased risk of miscarriage pregnancies. These include Cushing's syndrome, thyroid disease and polycystic ovary syndrome. It is further assumed that the malfunctioning corpus luteum in the ovaries (Body which produces progesterone hormone required for the maintenance of the very early stages of pregnancy) can lead to spontaneous abortion.

Infection during pregnancy with different types of disease-causing organisms also increases the risk of miscarriage. Examples of such infections are monotsitogenes listeria, toxoplasma gondiy, parvovirus B19, rubella, herpes simplex, cytomegalovirus and lymphocytic choriomeningitis virus. Abnormalities in the structure of the uterus also lead to abortion. In some women experience joint tissue (uterine septum) that separates the uterus sectors. Usually, this barrier is poorly vascularised and prevents attachment and growth of the placenta. Therefore, the embryo which is implanted in the septum is exposed to a higher risk of death due to spontaneous abortion.

Structural abnormalities are often the result of benign tumors in the uterus, known as fibroids. Fibroids (leiomyomata) are benign tumors made of muscle cells in the uterus. While most fibroids do not cause miscarriage (in fact they are very rare cause of infertility), a few of them may have an impact on the process of implantation of the embryo or disrupt the blood supply to the fetus, and thus lead to miscarriage.

Invasive surgical procedures affecting the uterus, such as amniocentesis and taking a tissue sample from the chorion (the outer covering of the fetus) also increase the risk of miscarriage.
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