Heart Rate

• Leptin can cause an increase in a person's heart rate. This is because medical injections of Leptin are meant to stimulate the metabolism. An increased metabolism can also lead to an increase in heart rate and blood pressure. These increases in heart rate and blood pressure should be minimal because leptin is only dispensed by licensed physicians. Any severe signs of heart rate increase, such as tightness in the chest, should be reported to the doctor who injected the leptin immediately.
  
  

Dehydration

• Leptin can cause an increase in the excretion of urine and the amount of perspiration produced by the body. This is because leptin increases energy expenditure by all systems of the body. To avoid dehydration while being injected with leptin, increase your fluid intake. Make sure to monitor perspiration and dehydration during strenuous activities when using it.
  
  

Nausea

• Leptin injections may cause nausea in some people. This may occur because the body is not used to an increased amount of Leptin being present. Your body should adjust to the presence of leptin within three to four days after being injected. If you continue to feel nausea while being injected with Leptin, ask your physician if alternate weight loss medications and treatment options are available.
  
  

Sleep Trouble

• Leptin injections can cause insomnia and other sleep complications in some people. This is because it has a stimulative effect on the body. If you experience sleeping complications while being injected with Leptin, inform the the physician performing the injections as soon as possible. They may lower the amount of your injections or suggest an alternate treatment program.
  
  

Hormonal Side Effects

• Leptin injections can increase the chance of pregnancy in women users. Leptin is sometimes used as part of a fertility treatment program. Ask for a consultation with your doctor if you are attempting to avoid pregnancy and receiving Leptin injections. You may wish to choose an alternate treatment program which does not increase the chance that you will become pregnant.