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Ixempra (Ixabepilone) -- Side Effects, Risks, and Recommendations

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Updated September 26, 2013.

Ixempra is a chemotherapy drug used to treat metastatic and locally advanced breast cancer. As with any drug, it carries risk of potential side effects -- not all of which will be experienced by everyone who takes it.

Common Side Effects of Ixempra



Possible Serious Side Effects of Ixempra

  • Neuropathy (nerve damage) in your hands and feet
  • Neutropenia (low white blood cell count; risk of infection)
  • Allergic reactions (itching; hives; rash; flushed face; heart palpitations; troubled breathing; swollen face, throat or tongue)

Other Risks of Using Ixempra

  • May cause harm to unborn baby
  • May leach into breast milk
  • Can cause adverse reactions in patients with cardiac disease

Do Not Take Ixempra If:

  • You have poor liver function
  • You have liver problems and already take capecitabine
  • You have an allergy to Cremophor EL or castor oil
  • Your white blood cell is lower than 1500 cells/mm3 or platelet counts are less than <100,000 cells/mm3
  • You are pregnant

Recommendations During Treatment

  • Use contraception to prevent pregnancy
  • Avoid grapefruit juice during an infusion, as it can amplify your side effects


  • Avoid driving or operating machinery, as the alcohol in Ixempra may cause drowsiness and dizziness

Ixempra - Description, Use, Dosage

Curious about potential side effects of other drugs? Check out About.com's Drug Finder.

Sources: FDA. Drugs@FDA. Ixempra Drug Details. Approved: October 16, 2007
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